Researchers sourcing Melanotan I for preclinical studies need a supplier that provides consistent quality, clear documentation, and the MC1R selectivity that distinguishes MT-1 from MT-2 in research applications. This guide covers supplier evaluation criteria and shows how Midwest Peptide meets those criteria for research grade MT-1 supply.
Where to Buy Melanotan I (MT-1) for Research: Sourcing Guide
Melanotan I · Published April 14, 2026 · Updated May 18, 2026 · 6 min read
Quick Answer
Researchers source Melanotan I (MT-1) from suppliers providing documented Certificate of Analysis, HPLC purity verification, and lot traceability for this MC1R-selective melanocortin agonist. This guide covers vendor evaluation and how Midwest Peptide MT-1 meets research-grade specifications. For research use only, not for human consumption.
Research Use Only. All products are strictly for research use only (RUO). Not for human consumption. Products on this site are not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA. By purchasing, you agree that you are a qualified researcher and that products will be used solely for in-vitro research purposes.
- What Research Grade MT-1 Supply Requires
- Sourcing Criteria for Research Grade MT-1
- Red Flags When Evaluating MT-1 Suppliers
- What MT-1 Is Studied For in Research
- Frequently Asked Sourcing Questions
- External Research Resources
- Related Research Reading
- Shop MT-1 at Midwest Peptide
- Related Research Articles
- Explore Related Products
- Frequently Asked Questions
- Glossary
Frequently Asked Questions
What is Melanotan I in research contexts?
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Melanotan I (afamelanotide) is a synthetic 13-amino-acid analog of alpha-melanocyte-stimulating hormone (alpha-MSH) with high MC1R selectivity. It is studied in preclinical research and clinical literature for melanogenesis, photoprotection, and erythropoietic protoporphyria.
What should researchers verify when sourcing Melanotan I?
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Verify HPLC purity above 98%, mass spec identity confirming the 13-amino-acid sequence with the Nle and D-Phe substitutions, peptide content quantification, endotoxin testing, and a recent batch-specific COA. Stability data is essential for the lyophilized form.
Where can research labs source verified Melanotan I?
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Midwest Peptide supplies research-grade Melanotan I (MT-1) with comprehensive COA documentation, HPLC purity verification, mass spec identity confirmation of the modified sequence, and lot tracking for reproducible MC1R selective melanocortin agonist research.
Is Melanotan I approved for human use?
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Glossary
Key terms used in this article.
- MC1R
- Melanocortin 1 receptor, the primary GPCR on melanocytes that signals melanin synthesis upon alpha-MSH binding.
- Melanogenesis
- The biochemical pathway producing melanin from tyrosine within melanosomes of melanocytes.
- Eumelanin
- The dark brown to black melanin pigment that provides photoprotective absorbance of UV radiation.
- Tyrosinase
- The rate-limiting copper-dependent enzyme catalyzing the first two steps of melanin biosynthesis from tyrosine.
- Erythropoietic Protoporphyria (EPP)
- A rare genetic disorder of heme biosynthesis causing severe photosensitivity, the indication for clinical afamelanotide use.
- Norleucine (Nle)
- A non-proteinogenic amino acid substitution at position 4 of Melanotan I that confers metabolic stability.
- D-Phenylalanine (D-Phe)
- The D-stereoisomer of phenylalanine substituted at position 7 of Melanotan I to enhance receptor potency.
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Research Use Only. All products are strictly for research use only (RUO). Not for human consumption. Products on this site are not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA. By purchasing, you agree that you are a qualified researcher and that products will be used solely for in-vitro research purposes.
