You must be 21 years or older to access this website. All products are for research use only.
Are you 21 years of age or older?
By entering, you confirm that you are at least 21 years old and agree to our terms of service.

Order before 2 PM CT — ships same business day
Volume Discount
8% off
$150+ cart
12% off
$250+ cart
18% off
$400+ cart
Third-Party Tested
Independent lab verification
COA Available
Certificate of Analysis included
Free Shipping
On all domestic orders
Research Use Only
For laboratory research purposes
Advance your laboratory studies with our Tesofensine (SNDRI) research-grade compound. This synthetic small molecule is specifically formulated to inhibit the reuptake of three primary neurotransmitters: serotonin, norepinephrine, and dopamine. This makes it an essential tool for investigating advanced metabolic regulation, appetite suppression pathways, and neuropharmacological synergy in controlled research models.
Each bottle contains 60 capsules, each standardized to a potent 500mcg dose, ensuring consistent data collection and precise titration across experimental trials.
Our Tesofensine capsules are engineered for specialized research into:
Neurotransmitter Modulation:
Examining the localized and systemic increase of extracellular monoamine concentrations and their impact on synaptic signaling.
Metabolic Rate & Energy Flux:
Investigating the compound’s influence on thermogenesis, oxygen consumption, and long-term energy expenditure homeostasis.
Satiety & Hypothalamic Pathways:
Assessing the inhibition of hunger-triggering neurons and the acceleration of satiety signaling in metabolic dysfunction models.
To ensure the longevity of the compound, store in a cool, dry place away from direct sunlight. For maximum long-term stability, refrigeration at 2°C–8°C is highly recommended. Always ensure the container is tightly sealed after use to prevent moisture contamination and maintain the integrity of the specialized oral formulation.
This product is strictly for RESEARCH USE ONLY.
It is not intended for human consumption, nor for any diagnostic, therapeutic, or clinical applications. This material must be handled by qualified professionals in a controlled laboratory setting.
Tesofensine is a small-molecule research compound classified as a triple monoamine reuptake inhibitor (SNDRI), studied for its effects on serotonin, norepinephrine, and dopamine transporters. Supplied here in standardized 500mcg capsules with >=99% purity for laboratory research only.
Tesofensine is studied in preclinical research on monoamine transporter pharmacology, central nervous system reuptake mechanisms, and metabolic regulation pathways. All cited studies are conducted in rodent or in-vitro systems consistent with the molecule's RUO classification.
Selective inhibitors target a single transporter (SERT, NET, or DAT), while tesofensine inhibits all three (SNDRI). Research models show the multi-transporter mechanism produces a different neurochemical profile than selective compounds.
Other research peptides in this category
Research Use Only. These products are not supplements, drugs, or intended for human or veterinary use. These products are for laboratory research purposes only. All product information available on this website is for educational purposes only. The products offered on this website are not intended to diagnose, treat, cure, or prevent any disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This material is sold for in-vitro research purposes only.
High-purity Tesofensine, a potent triple monoamine reuptake inhibitor (SNDRI) for advanced laboratory research. Each 60-count bottle provides standardized 500mcg units with 99%+ purity, optimized for oral administration studies involving neurotransmitter modulation and metabolic pathways. DISCLAIMER: RESEARCH USE ONLY. Not for human consumption, clinical, or therapeutic use. Conduct experiments in controlled environments only. All Midwest Peptide products are 3rd-party verified to ensure consistency in your research protocols.
Add $20.01 more to save 8% off
Research Use Only. This product is intended solely for laboratory research purposes. Not for human or veterinary use. Not for food or cosmetic use. By purchasing, the buyer agrees to use this product only for research applications.
Every batch of tesofensine capsules ships with a third-party COA verifying purity by HPLC (>=99%), identity by mass spectrometry, and per-capsule mass. The batch-specific COA is published on this product page before purchase.
Store sealed at 2-8C, protected from light and humidity. Once the bottle is opened, keep tightly closed and use within the period indicated on the COA. Avoid exposure to direct heat.
Tesofensine is not FDA-approved. It has been investigated in clinical research but is not currently a therapeutic. The capsules supplied here are for laboratory and research use only and are not approved for diagnostic, therapeutic, or human use.