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A selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) that modulates NAD+ salvage and lipogenesis pathways in preclinical metabolic research models. Premium Research Peptide.
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⚠️ Legal Disclaimer: The statements provided and this compound have not been evaluated by the U.S. Food and Drug Administration. No claims are made regarding diagnosis, treatment, or prevention of any disease. Use is restricted to qualified researchers operating in certified laboratory environments.
Terms of Sale: By purchasing from Midwest Peptide, the buyer affirms they are a qualified researcher or institutional purchaser, fully responsible for proper handling, storage, and legal compliance. All sales are final.
5-Amino-1MQ is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). It is a research compound studied for its effects on NAD+ salvage pathways, methyl donor balance, and metabolic regulation. Supplied strictly for Research Use Only.
NNMT (nicotinamide N-methyltransferase) is an enzyme that methylates nicotinamide using S-adenosylmethionine, producing 1-methylnicotinamide. Inhibiting NNMT alters NAD+ salvage flux and methyl donor pool balance, which is the research basis for studying 5-Amino-1MQ in metabolic and epigenetic models.
5-Amino-1MQ is studied in preclinical research on NNMT enzyme inhibition, NAD+ pathway dynamics, adipose tissue metabolic research, and methyl donor pool regulation. All cited studies are conducted in cellular or rodent systems consistent with RUO classification.
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Research articles and insights related to 5-Amino-1mq

A research review of 5-Amino-1MQ adipocyte and metabolic studies covering NNMT expression in adipose tissue, cellular energy metabolism, and rodent model literature. For research use only.
June 16, 2026

A research review of how 5-Amino-1MQ inhibits NNMT and the downstream effects on NAD+ salvage and S-adenosylmethionine methylation metabolism in preclinical models. For research use only.
June 16, 2026

A research review of 5-Amino-1MQ, a small-molecule NNMT inhibitor, covering its proposed mechanism, NAD+ and methylation metabolism, and adipocyte research studies. For research use only.
June 16, 2026
Research Use Only. These products are not supplements, drugs, or intended for human or veterinary use. These products are for laboratory research purposes only. All product information available on this website is for educational purposes only. The products offered on this website are not intended to diagnose, treat, cure, or prevent any disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This material is sold for in-vitro research purposes only.
Every batch of 5-Amino-1MQ ships with a third-party COA verifying purity by HPLC (>=99%), identity by mass spectrometry, and lyophilized mass. The batch-specific COA is published on this product page before purchase.
Store at -20C for long-term storage and 2-8C for short-term use within 30 days. Avoid repeated freeze-thaw cycles. Store in original sealed vials, protected from light.
5-Amino-1MQ is not FDA-approved and is a research compound. The product supplied here is for laboratory and research use only and is not approved for diagnostic, therapeutic, or human use.